Cdx2 binding motif
WebApr 10, 2024 · Sequence analysis identified six potential CDX2-binding sites within the IL33 ChIP-seq peak, indicating a potential regulatory region (Fig. 1B). After validating that CDX2 binds in the potential enhancer using quantitative PCR of CDX2-precipitated chromatin from LS174T cells (Fig. 1C ), we investigated to which extent CDX2 regulates IL33 ...
Cdx2 binding motif
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WebMar 27, 2014 · Condition-independent Cdx2 binding is associated with higher cognate motif affinity. Since condition-specific Cdx2 binding events appear highly correlated … WebJun 30, 2009 · We found that Nanog, Oct4 and Cdx2 bind to the promoter and the intron 1 of the Cdx2 gene ( Figure 2 ). The binding pattern for Nanog is similar to Oct4. Both factors bind to region 4 in the Cdx2 ...
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WebMar 1, 2024 · DNA-binding motif analyses (Figs 2, 3) suggest that CDX2 has different binding partners in embryonic versus mature intestine, and that these partners are likely … WebCDX2 ChIP-Seq signal higher than the CDX2 signal threshold; binding sites unique to HNF4A are defined similarly. Because we observed quan-titative continua of TF binding, these thresholds allow more stringent categorization of binding events as solitary or cooccupied. Genomic re-gions with high H3K4me2 signal but no CDX2 or HNF4A …
WebMultiGPS results (Cdx2) ... --verbose --probshared 0.99 --memepath software/meme_4.9.0/bin --mememinw 6 --mememaxw 16 --seq genomes/mm9 --out Cdx2 Binding events. Condition ... Try inputting these motifs into STAMP for validation. Peak-peak distance histograms (same condition)
WebAug 27, 2004 · As shown in Fig. 3B, both of the Cdx2 and Cdx1 expression led to active transcription significantly by the minimal sucrase-isomaltase promoter containing one Cdx-binding motif. On the other hand, Cdx2 expression activates transcription by the MOK promoter significantly, whereas the Cdx1 expression exhibited quite a low transcription … corporate defence networkWeb(C) Histone H3 ChIP analysis at the Oct-Sox binding motif in Oct4 and Nanog at 0, 48, and 96 h after induction of Cdx2. The enrichment of histone H3 on Gapdh was utilized as a control. far away tab nickelbackWebAug 17, 2024 · Figure S3 ChIP-seq analysis showing (a) Cdx2 genomic distribution. (b) De-novo Cdx2 binding motif analysis. mmc4.pdf (116K) GUID: 46DE217C-B56C-4537-807A-4DECD2EC3022 ... Examination of the TRIM31 locus revealed a major Cdx2 binding peak within the promoter region (Fig. 4 C) with occupancy confirmed by ChIP–PCR (Fig. S5A). faraway suitesWebJan 22, 2024 · Potential CDX2-binding sites were identified in the MUC2 promoter using bioinformatics analysis. To further demonstrate that CDX2 transcriptionally activated MUC2 expression by binding to the ATAAA motif in the MUC2 promoter, the MUC2 promoter luciferase construct was used to produce a mutant construct. far away televisionWebBest Cinema in Fawn Creek Township, KS - Dearing Drive-In Drng, Hollywood Theater- Movies 8, Sisu Beer, Regal Bartlesville Movies, Movies 6, B&B Theatres - Chanute Roxy … faraway testoWebNov 1, 2012 · The Cdx2 consensus and binding motifs within Xist intron 1, Xite, and HoxC8 (a known Cdx2 target gene) are shown. (B) qChIP analysis of Oct4 and Cdx2 binding at designated sites in the indicated cell lines. ES, Cdx2-transgenic ES clones without Tx induction of Cdx2. iTS, Cdx2-transgenic clones transdifferentiated to TS cells … far away ters letraWebMay 26, 2024 · Accordingly, we examined the genome-wide occurrence of TF binding motifs in organ-specific open chromatin regions and identified those TFs whose motifs occurred in the chromatin regions that ... far away teller