Dynamo mapping vector field of single cells
WebAug 22, 2024 · Dynamo: Mapping Transcriptomic Vector Fields of Single Cells. Inclusive model of expression dynamics with metabolic labeling based scRNA-seq / multiomics, vector field reconstruction, potential landscape mapping, differential geometry analyses, and most probably paths / in silico perturbation predictions. WebFeb 2, 2024 · Researchers at the Whitehead Institute for Biomedical Research and other centers describe a computational approach called dynamo, which they used to retrace RNA velocity and single-cell transcriptomic "vector fields," and regulatory features from time-resolved single-cell RNA sequence data. "This framework represents a notable advance …
Dynamo mapping vector field of single cells
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WebFeb 9, 2024 · Here, we introduce dynamo, an analytical framework that reconciles intrinsic splicing and labeling kinetics to estimate absolute RNA velocities, reconstructs velocity … WebInclusive model of expression dynamics with metabolic labeling based scRNA-seq / multiomics, vector field reconstruction and differential geometry analyses - GitHub - KBRI-Biology-Experiment-Comput...
WebAug 8, 2024 · In large datasets, it is easier to visualize the prevalent pattern of cell velocities with locally averaged vector fields (Fig. 2i). Because cells can have RNA velocities along multiple ... http://dynamo-readthedocs.readthedocs.io/
WebInclusive model of expression dynamics with metabolic labeling based scRNA-seq / multiomics, vector field reconstruction and differential geometry analyses - dynamo-release-Mapping-Vector-Field-of-... WebFeb 18, 2024 · To enable such temporal analysis from multimodal single-cell experiments, we introduce an extension of the RNA velocity method that leverages estimates of unprocessed transcript and protein abundances to extrapolate cell states. ... Wang L, Yuan R, et al. Mapping Vector Field of Single Cells. Biorxiv. 2024;9:696724. Google Scholar …
WebJul 9, 2024 · Here, we introduce dynamo, an analytical framework that reconciles intrinsic splicing and labeling kinetics to estimate absolute RNA velocities, reconstructs velocity …
WebLeveraging the least-action-path method, dynamo accurately predicts drivers of numerous hematopoietic transitions. Finally, in silico perturbations predict cell-fate diversions induced by gene perturbations. Dynamo, thus, represents an important step in advancing quantitative and predictive theories of cell-state transitions. small realistic electric fireplacehttp://dynamo-readthedocs.readthedocs.io/ small real looking baby dollsWebJul 9, 2024 · Abstract. Single-cell RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however ... small realistic bloxburg houseWebJul 9, 2024 · Single-cell RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these … small real wood dining tableWebFeb 1, 2024 · Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however, requires ... small reaper scythe crochetWebMar 31, 2024 · Wagner, D. E. et al. Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo. Science 360, ... Qiu, X. et al. Mapping vector field of single cells. small real potted christmas treeWebDynamo: Mapping Vector Field of Single Cells. Single-cell RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented … small real xmas trees