Flotillin complex

Author: vmwu

August undefined, 2024

WebLack of flotillin leads to coalescence of distinct domains of high membrane order and reduces the heterogeneity of membrane lipid types. . Another flotillin role is to facilitate efficient protein complex assembly, which is probably why flotillin perturbation affects the function of FMM-associated signal transduction pathways[5,54,57]. WebDec 13, 2002 · Plasma membrane association of both full-length flotillin and the green fluorescent protein-tagged PHB domain of flotillin is dependent on palmitoylation and …

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WebMar 21, 2024 · ATP-binding cassette, sub-family A (ABC1), member 1 forms a complex with syntaxin 13 and flotillin-1, residing at the plasma membrane and in phagosomes; Flotillin-1, a marker of rafts, accumulates in lysosomes of neurons in Alzheimer's disease; Recombinant flotillin-1 was purified and characterized in in large quantity and high purity. WebThe formation of the face in vertebrate animals is a complex and precisely orchestrated process involving the sequential migration, proliferation and … smart goals for nursing educators

Flotillin-1-enriched Lipid Raft Domains Accumulate on Maturing ...

WebTwo flotillin members have been described, flotillin-1 and flotillin-2. In addition to its colocalization with lipid rafts on the plasma membrane, flotillin-1 also has been found in compartments of the endocytic and autophagosomal pathways, such as recycling/late endosomes, the Golgi complex, and the nucleus (6,7). WebAug 6, 2012 · Furthermore, flotillin-1 and -2 were found to be in a molecular complex with ErbB2 and Hsp90. The depletion of one of these proteins results in disruption of this complex, followed by ... WebWestern blot was performed using Anti- Flotillin 1 Polyclonal Antibody ( Product # PA5-19713) and a 47kDa band corresponding to Flotillin 1 was observed across all the cell … smart goals for nursing students on placement

Exploring functional membrane microdomains in bacteria: an …

Flotillin-mediated endocytosis and ALIX–syntenin-1

WebFlotillin-mediated endocytosis and ALIX–syntenin-1–mediated exocytosis protect the cell membrane from damage caused by necroptosis Weiliang Fan1,2, ... for the cross-linking and tandem affinity purification of the lipid raft–bound phospho-MLKL protein complex. TSZ, TNF (20 ng/ml), Smac mimetic (100 M), and z-VAD (20 M); DSP, dithiobis ... WebFeb 9, 2024 · Using site-specific mapping, we also uncovered that the SPFH (stomatin, prohibitin, flotillin, and HflK/C) domain of flotillin-1 interacted with TRPV2 N-termini and transmembrane domains 1-4, respectively. Our findings therefore demonstrate that flotillin-1 is a key element in TRPV2 signaling complex and modulates its cellular response. hills science diet high energy dog foodWebFeb 4, 2024 · Folkston-area complex now counts 3,018 beds near a city with about 4,400 residents. A corrections company has reached an agreement with local officials that … hills science diet urinary c/d for dogs

"WebFlotillin-1 was recently shown to be enriched on detergent-resistant domains of the plasma membrane called lipid rafts. These rafts, enriched in sphingolipids and cholesterol, … " - Flotillin complex

Flotillin complex

ERLIN2 Recombinant Monoclonal Antibody (JE57-03) (MA5-44911)

WebPart of flotillin complex. Is active in glutamatergic synapse and presynaptic active zone membrane. Orthologous to human FLOT2 (flotillin 2); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8 … WebJul 3, 2024 · Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with obesity. They are accompanied by increased levels of free cholesterol in the liver. Most free cholesterol resides within the plasma membrane. We assessed the impact of adding or removing free cholesterol on the function and …

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WebCadherin-1 or Epithelial cadherin (E-cadherin), (not to be confused with the APC/C activator protein CDH1) is a protein that in humans is encoded by the CDH1 gene. Mutations are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers.CDH1 has also been designated as CD324 (cluster of differentiation 324). It is a tumor suppressor gene. Webhetero-oligomeric complex that contains both caveolins 1 and 2. However, protein levels of flotillin-1 and flotillin-2/ESA remain unchanged in response to oncogenic …

WebSep 18, 2012 · We recently identified flotillin-1 as a key regulator of EGF receptor and the downstream mitogen activated protein kinase (MAPK) ERK1/2 signaling. In this cascade, … WebJan 1, 2024 · Flotillin-2 was originally cloned in 1994 by Schroeder et al. by immunoscreening of a human keratinocyte cDNA library using the monoclonal antibody ECS-1 against cultured keratinocytes. ... palmitoylation, and hydrophobic interaction. Flotillin-2 is mainly found in a hetero-oligomeric complex with its homologue flotillin-1, …

WebDec 7, 2011 · They demonstrated that flotillin-1 forms a ternary complex with c-Cbl-associated protein (CAP) and the E3 ubiquitin protein ligase Cbl upon insulin stimulation (Figure 5). This was shown to be important for lipid raft association, downstream signaling of the CAP-Cbl complex and finally for glucose uptake by the glucose transporter GLUT4 … WebTranscripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

• Schroeder WT, Stewart-Galetka S, Mandavilli S, et al. (1994). "Cloning and characterization of a novel epidermal cell surface antigen (ESA)". J. Biol. Chem. 269 (31): 19983–91. doi:10.1016/S0021-9258(17)32117-8. PMID 8051082. • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

WebTwo flotillin members have been described, flotillin-1 and flotillin-2. In addition to its colocalization with lipid rafts on the plasma membrane, flotillin-1 also has been found in compartments of the endocytic and … hills science diet small bites puppy foodWebApr 5, 2024 · Immunoglobulin G subclasses of anti-flotillin-1/2 antibodies were predominantly 1 and 3. We confirm that antibodies targeting the flotillin-1/2 complex are present in a subgroup of patients with ... hills science diet minced cat foodWebcomplex subunit μ2; Flot, flotillin; Tnr, transferrin receptor. (B–E) Cholesterol-regulated recycling of flotillin-1 is depen-dent on NPC1L1. (B and C) Flotillin-1-RFP was … hills science diet perfect weight wethttp://amigo.geneontology.org/amigo/term/GO:0016600 smart goals for operating room nursesWebAbout. LakePoint Sports, the premier travel and youth sports destination in the country, serves athletes in more than 30 sports year-round, including baseball, basketball, volleyball, soccer, lacrosse, football, gymnastics … smart goals for online learning examplesWebJun 23, 2024 · Flotillin-1 and Flotillin-2 (synonyms: reggie-2 and reggie-1) were originally described to be upregulated in regenerating axons of goldfish retinal ganglion cells after … hills science diet multi benefit w/dhttp://amigo.geneontology.org/amigo/term/GO:0016600#:~:text=A%20protein%20complex%20that%20contains%20flotillin-1%20and%20flotillin-2%2C,proteins.%20Flotillins%20associate%20into%20membrane%20microdomains%20resembling%20caveolae. hills science diet id dry food