WebTransferrin receptor (TfR) expression is regulated by the iron regulatory protein system.94,99 Iron accumulation has been associated with cell damage, so the TfR … Web17 Mar 2024 · The transferrin receptor 1 (TfR1), also known as cluster of differentiation 71 (CD71), is a type II transmembrane glycoprotein that binds transferrin (Tf) and performs a critical role in cellular iron uptake through the interaction with iron-bound Tf. Iron is required for multiple cellular processes and is essential for DNA synthesis and, thus, cellular …
Frontiers Antibodies Targeting the Transferrin Receptor …
Web13 May 2024 · Transferrin receptor (TFRC) is the major mediator for iron entry into a cell. Under excessive iron conditions, TFRC is expected to be downregulated via the iron regulatory protein and the iron-responsive element machinery to … WebTFRC is a Diagnostic and Prognostic Indicator. Firstly, we use TCGA and GEO database to build ROC curve, and found the AUC = 0.856 (GSE16515) and 0.742 (TCGA and GTEx), … flaticon gym
TFRC protein expression summary - The Human Protein Atlas
Web1 Nov 2016 · TfR1 is encoded by the TfRC gene that belongs to the transferrin receptor family. The family of receptors includes TfR2 and is derived from ancient … Web16 Mar 2024 · The bioinformatics analysis showed that TFRC plays a role in the occurrence and development of pancreatic cancer mainly through signaling pathways (including cell adhesion molecule binding, condensed chromosomes, chromosome segregation, and cell cycle checkpoints). Web17 Jan 2024 · Transferrin receptor (TFRC), which was overexpressed in cervical cancer and involved in the HIF-1 pathway, was associated with advanced clinical pathologic … flat icon free